[NumLock]

для Ctrl+F1 и Ctrl+F2 :

Код:

unit Unit1;

interface

uses
  Windows, Messages, SysUtils, Variants, Classes, Graphics, Controls, Forms,
  Dialogs;

type
  TForm1 = class(TForm)
    procedure FormDestroy(Sender: TObject);
    procedure FormCreate(Sender: TObject);
  private
    { Private declarations }
  public
    { Public declarations }
    procedure WMHOTKEY(var Message: TWMHotKey); message WM_HOTKEY;
  end;

var
  Form1: TForm1;

implementation

{$R *.dfm}

procedure TForm1.FormCreate(Sender: TObject);
begin
  RegisterHotKey(Handle, 1, MOD_CONTROL, VK_F1);
  RegisterHotKey(Handle, 2, MOD_CONTROL, VK_F2);
end;

procedure TForm1.FormDestroy(Sender: TObject);
begin
  UnregisterHotKey(Handle, 1);
  UnregisterHotKey(Handle, 2);
end;

procedure TForm1.WMHOTKEY(var Message: TWMHotKey);
begin
  case Message.HotKey of
    1: ShowMessage('1');
    2: ShowMessage('2');
  end;
end;

end.